急危重症吸附解决计划

急危重症吸附解决计划

重症患者机体受到熏染之后，炎性反应呈级联式放大，而人体为对抗炎症反应而形成的代偿性反应综合征，一旦患者爆发全身性炎性反应与代偿性抗炎反应杂乱，可以导致其体内的情形稳态被破损，泛起组织损伤，最终泛起多种器官的功效衰竭^[1]。97国际公司针对差别类型危重症患者提供吸附解决计划，97国际HA一次性血液灌流器，原研经典，广谱吸附，有用扫除以炎症介质为代表的中大分子，可用于脓毒症^[2-3]、重症急性胰腺炎（SAP）^[4-5]、急性呼吸拮据综合征（ARDS）^[6-7]等炎症因子相关性疾病及心外科手术患者^[8]；CA330细胞因子吸附柱，中国首个获批医疗器械注册证的细胞因子吸附类产品，专用于脓毒症患者炎症早期或细胞因子风暴期。血液吸附危重症领域治疗模式多样，临床上可以凭证现真相形单独灌流使用，也可与其他血液净化模式团结使用，如HP+HD/HDF/CVVH、PFAD/CPFA^[17]、(PFAD-HD)/ CPFA-CRRT^[17]、HP+CPB、HP+ECMO，举行全血或者血浆灌流治疗。

参考文献：
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[2]Zhao Huang, Si-rong Wang, Zi-li Yang, and Ji-yun Liu. Effect on Extrapulmonary Sepsis-Induced Acute Lung Injury by Hemoperfusion With Neutral Microporous Resin Column[J]. Therapeutic Apheresis and Dialysis, 2012:1-8.
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[6]Xu, Xuefeng, et al. "Effect of HA330resin-directed hemoadsorption on a porcine acute respiratory distress syndrome model." Annals of intensive care 7.1 (2017): 84.
[7]Li, Cong, Nana Xu, and Tie Xu. "Therapeutic Effects of Hemoperfusion Combined with High Volume Hemofiltration on Acute Respiratory Distress Syndrome Short Title: Treatment of ARDS." Revista Argentina de Clinica Psicológica 29.3(2020):311.
[8]Zijian He, etal. The Efficacy of Resin Hemoperfusion Cartridge on Inflammatory Responses during Adult Cardiopulmonary Bypass. Blood Purif.2021 Jun 9;1-7.
[9]ZHANG Lin,et al.Clinical study of mechanical ventilation combined with hemoperfusion and purification in the treatment of pneumothorax complicated by respiratory failure caused by traffic accident.Chin J Emerg Resusc Disaster Med.2021.
[10]Yuan,Hai,et al."Efficacy of two combinations of blood purification techniques for the treatment of multiple organ failure induced by wasp stings."Blood Purification 42.1 (2016):49-55.
[11]Zijian He,et al.The Efficacy of Resin Hemoperfusion Cartridge on Inflammatory Responses during Adult Cardiopulmonary Bypass.Blood Purif.2021 Jun 9;1-7.
[12]Xu,Xuefeng,et al."Effect of HA330 resin-directed hemoadsorption on a porcine acute respiratory distress syndrome model."Annals of intensive care 7.1 (2017):84.
[13]Li,Cong,Nana Xu,and Tie Xu."Therapeutic Effects of Hemoperfusion Combined with High Volume Hemofiltration on Acute Respiratory Distress Syndrome Short Title:Treatment ofARDS."Revista Argentina de Clinica Psicológica 29.3 (2020):311.
[14]Wang,Y.T.,et al."Effects of hemodialysis and hemoperfusion on inflammatory factors and nuclear transcription factors in peripheral blood cell of multiple organ dysfunction syndrome."Eur Rev Med Pharmacol Sci 20.4 (2016):745-50.
[15]Huang Bin,et al.Clinical study of continuous veno-venous hemofiltration combined with hemoperfusion in the treatment of severe burn sepsis.Journal of Clinicalemergency(China).2019:1009-5918.
[16]Prof.Claudio Ronco.CENTRO SPECIALIZZATO REGIONALE.PER LE TERAPIE DIALITICHE NELL'INSUFFICIENZA RENALE ACUTA E CRONICA E PER LE TECNOLOGIE EXTRACORPOREE di SUPPORTO MULTI-ORGANICO.2020.
[17]Ronco, C., & Bellomo, R. (2022). Hemoperfusion: technical aspects and state of the art. Critical care (London, England), 26(1), 135. https://doi.org/10.1186/s13054-022-04009-w.

临床应用

急性中毒吸附解决计划

血液灌流可用于人体内内源性和外源性代谢产品、毒物及余量药物的扫除,已被写入多项急性中毒专家共识，针对种种急性中毒患者，HA一次性血液灌流器，原研经典，足程净化，可用于有机农药中毒^[1-5]、药物中毒^[6-7]、除草剂中毒^[9-13]、毒蕈中毒^[14-16]、蜂蛰伤^[17]等急性中毒的抢救治疗。临床上可以使用多类血液净化动力装置单独灌流使用，也可与其他血液净化器团结使用，举行全血或者血浆灌流治疗�？稍诠嗔骰�(JF-800A),Future F20血液净化装备、透析机、CRRT机（如97国际DX-10）等多种血液净化装备上完成治疗。

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